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The P-Shot vs Medication for Peyronie’s Disease: Which is Best?

what is p-shot

Peyronie’s disease is a complex condition to live with. It causes discomfort, self-consciousness and, for some, physical limitations. The quest for effective treatment can be a long one, and for many patients, effective medication for Peyronie’s disease is very difficult to find. 

Often, people are left deciding between these two main options: medications and the P-Shot. This blog will compare the two and help you make an informed decision for your treatment so that you can manage this condition as effectively as possible.

What is Peyronie’s Disease?

Peyronie’s disease is a condition resulting from scar tissue that develops on the penis and causes curved, painful erections. The condition affects as many as 1 in 11 men.

Having a curved penis is not unusual. However, the bend becomes significant for Peyronie’s sufferers, and it usually causes painful erections, preventing you from having sex or making it very difficult to get or maintain an erection.

Extreme symptoms can have a considerable impact on life and general well-being. While some cases may improve on their own, treatment is usually essential to effectively manage symptoms and prevent further progression of the disease.

Traditional Medication for Peyronie’s Disease

Several traditional medications can be used to treat the symptoms of Peyronie’s disease, including:

Oral Medications:

While not a primary treatment for Peyronie’s disease, a doctor can prescribe certain oral medications to help manage symptoms or support other therapies:

  • Pentoxifylline: This works by improving blood flow and reducing inflammation. There are some potential side effects, including nausea and dizziness. However, patients often report limited effectiveness in reducing curvature.
  • Tadalafil: This is a daily medication that improves blood circulation to the penis, potentially slowing the progression of scarring. It may help reduce pain and improve erectile function. The side effects are generally mild, including headache, back pain, or muscle aches.
  • Colchicine: This is an anti-inflammatory medication prescribed to reduce swelling. Some studies show this medication has the potential to improve penis curvature. But, like all studies, many others show no significant difference. Potential side effects include nausea, vomiting, diarrhoea, and abdominal pain. You should only use it under the guidance of a healthcare professional.
  • Carnitine: This is an amino acid naturally produced by the body. The amino acid has antioxidant and anti-inflammatory properties with some research suggesting it could help reduce pain and improve erectile function. It’s worth noting, however, that these studies are minimal.
  • Tamoxifen: This medicine is primarily used to treat breast cancer but has also been studied for its potential role in helping Peyronie’s disease. It may help reduce inflammation and increase collagen production, slowing down plaque formation. There is little research to confirm its effectiveness, and it can cause significant side effects, especially when taken long-term.

Injectable Medications:

As well as taking tablets, your doctor could prescribe injectable medicines, such as Xiaflex (collagenase clostridium histolyticum)

This is the only FDA-approved injectable medication for Peyronie’s disease and breaks down collagen in the plaque, reduces penile curving, and improves erectile function. Side effects include bruising, swelling, and pain. Multiple injections are typically needed over several months.

The P-Shot: A Natural Alternative To Medication For Peyronie’s Disease

The P-Shot is a pioneering treatment for Peyronie’s disease. It can correct a bend in the penis by helping to tackle the excessive plaque build-ups.

The P-Shot uses platelet-rich plasma found in your blood to stimulate the growth of new, younger tissue and increase blood flow. PRP treatments have been used successfully to repair damaged muscles and nerves for many years and can ease Peyronie’s symptoms significantly

PRP contains cell-regenerating growth factors that are essential for treatment and the procedure works by taking a small amount of your blood, which is then spun at a high frequency within a centrifuge to separate the platelet-rich plasma (PRP). 

Your doctor will inject this serum into your treatment area. This might sound uncomfortable, but the whole procedure is done under local anaesthetic, so there is little to no pain.

medication for Peyronie's disease1

Benefits of The P-Shot For Peyronie’s Disease

There are many benefits of choosing the P-Shot as medication for Peyronie’s disease, including promoting tissue regeneration and repair, reducing inflammation and pain, and improving blood flow and erectile function.

The following will compare and contrast the different treatment options so that you can choose which could work best for you.

P-Shot Advantages Over Medication For Peyronie’s Disease

Compared to taking prescribed medication, the P-Shot has an advantage because it utilises your body’s natural healing mechanisms for a more organic approach. The results are typically longer-lasting, with fewer potential side effects.

Comparing the Two: P-Shot vs Medication

Benefits of The P-Shot

  • Promotes natural tissue regeneration and repair.
  • Reduces inflammation and pain.
  • Improves blood flow and overall erectile function.
  • Patients experience minimal downtime and side effects.

Drawbacks

  • Multiple sessions are usually needed as results last up to 18-24 months.
  • The P-Shot may be more expensive than some medications.

Benefits of Medication

  • Medications like Xiaflex directly target the collagen in the plaque, potentially leading to a reduction in curvature. However, this is not available in the UK.
  • Xiaflex is the only FDA-approved medication specifically for Peyronie’s disease.
  • Oral and injectable medications offer a non-surgical approach to treatment.

Drawbacks

  • Some oral medications may have limited effectiveness in significantly reducing curvature.
  • Medications can have various side effects.
  • Multiple injections or long-term use.
  • Not suitable for everyone: Some medications may not be appropriate for individuals with certain medical conditions or when taking other medications.

Next Steps For Peyronie’s Treatment? 

While medications offer a traditional approach to managing Peyronie’s disease, the P-Shot presents a natural and potentially longer-term solution. 

If you’re seeking relief from the symptoms of Peyronie’s and want to explore a drug-free option, the P-Shot could be the answer you’ve been looking for.

Elite Aesthetics specialises in men’s intimate health, and Dr Shirin is an accredited non-surgical doctor with over 20 years of experience, including several years as a practising GP. If you want to learn more about the medication for Peyronie’s disease, then you should book a consultation with her. All our consultations are at our clinic in Greenhithe, Kent, just 22 minutes away by train from St. Pancras, London. 

You can contact us by calling 01322 381 205, emailing info@elite-aesthetics.co.uk, or WhatsApp us. 

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